Magnesium L-threonate (Magtein®)

Magnesium L-threonate Magtein® – The magnesium that thinks of you

Magnesium L-threonate (Magtein®) from EssentialSeries is a magnesium-based food supplement.

Magtein® is a patented form of magnesium L-threonate created to make the most of magnesium’s properties as a mineral. The aim of magnesium threonate is clear: to contribute to the normal functioning of the nervous system and help reduce tiredness and fatigue. Thanks to its properties, Magtein® helps magnesium work to its full potential in the nervous system, compared with conventional salts such as bisglycinate or citrate.

The form matters. Magtein® makes the difference.

Why threonate is different

L-threonic acid is a natural metabolite of vitamin C that acts as a carrier. When it binds to magnesium, it forms a complex.

This makes Magtein® a good choice when you want to supplement your diet with magnesium.

Magtein® quality – Discover it

Magtein® is a patented ingredient developed by ThreoTech LLC with purity, identity and stability controls. Its production is protected to ensure the same composition in every batch of raw material.

2000 mg dose of magnesium threonate

Each serving (3 vegetable capsules) provides 2000 mg of Magtein®, equivalent to 144 mg of elemental magnesium. This serving size has been set by the HSN R&D specialists.

Key benefits of magnesium

•  Helps reduce tiredness and fatigue.
•  Contributes to electrolyte balance.
•  Contributes to normal energy-yielding metabolism.
•  Supports the normal functioning of the nervous system and muscles.
•  Contributes to normal protein synthesis and normal psychological function.
•  Helps maintain normal bones and teeth.
•  Plays a role in the process of cell division.

Magnesium threonate is a form of magnesium associated with nervous system support and psychological function.

Clean label: HSN purity and quality

At HSN, we’re committed to developing clean-label formulas. Our magnesium threonate comes in vegetable capsules (no gelatine), with minimal additional ingredients, no colourings or unnecessary additives, and 0 % cosmetic ingredients. It’s 100 % vegan, allergen-free and free from genetically modified organisms.

Easy to fit into your day

The daily serving of 3 capsules, taken all at once, makes it easy to enjoy magnesium threonate. You can take them with or without food, although taking them with a meal may be preferable.

How can you make the most of magnesium threonate?

Magnesium provides nutritional support with continued use: consistency is key. Maintaining adequate mineral levels in the body matters, and if your diet isn’t particularly rich in magnesium, magnesium threonate is an ideal way to supplement it.

Advantages over other mineral salts

Oxide, citrate and bisglycinate are commonly used magnesium salts that can help improve overall mineral status, but they’re not as specifically associated with neurological and psychological functions. Magtein®, as a patented form of magnesium threonate, is: its structure lets you make the most of its properties.

If you want to support your nervous system* by supplementing your diet with magnesium, L-threonate is a good choice.

* Magnesium contributes to the normal functioning of the nervous system.

Who is it ideal for?

People looking for general nervous system support or daily support for psychological function by supplementing their diet with magnesium.

What can you combine it with?

Magnesium threonate can be combined with choline or caffeine if you’re a student.

You can also combine it with electrolytes or creatine if you use magnesium threonate for sport or as part of a wider supplement routine.

If you’re looking for a combined formula with Magtein®, ATA Mg® and vitamin B5, check out our CogniMag capsules.

Commitment to quality – Magtein® × HSN

We use Magtein® raw material because it’s one of the most internationally recognised patented ingredients for quality and transparency in production.

At HSN, we’re committed to bringing you products at a fair price. We choose the best raw materials, manufacture under the highest quality controls and get your products to you quickly.

Frequently asked questions (FAQ)

Why choose Magtein® over other threonates?

Magtein® is a patented form of L-threonate backed by specific studies in particular areas, ensuring the production process meets unquestionable quality standards.

Is a dose of 144 mg of elemental magnesium enough?

Yes. With magnesium threonate, unlike other salts, the serving size focuses on the complete salt rather than just its elemental magnesium content. Even so, 144 mg of elemental magnesium is a meaningful amount, provided by 2000 mg of magnesium threonate.

When can you expect results?

It depends on your existing magnesium status and other factors. Scientific studies assessing the potential of magnesium threonate often have an intervention period of 8 to 12 weeks, so this is a useful guide to when you might expect the full nutritional support of daily magnesium use.

A quick summary to keep everything handy

•  Main ingredient: Magtein® (magnesium L-threonate), a patented ingredient.
•  Daily amount: 2000 mg of Magtein® = 144 mg of elemental magnesium.
•  Purpose: normal functioning of the nervous system and normal psychological function.
•  Formula: clean label, vegan, GMO-free and allergen-free.

Scientific references

•  Zhang, C., Hu, Q., Li, S., Dai, F., Qian, W., Hewlings, S., Yan, T., & Wang, Y. (2022). A Magtein®, Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults. Nutrients, 14(24), 5235.
•  Hausenblas, H. A., Lynch, T., Hooper, S., Shrestha, A., Rosendale, D., & Gu, J. (2024). Magnesium-L-threonate improves sleep quality and daytime functioning in adults with self-reported sleep problems: a randomized controlled trial. Sleep Medicine: X, 8, 100121.
•  EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) (2024). Safety of magnesium l-threonate as a novel food pursuant to regulation (EU) 2015/2283 and bioavailability of magnesium from this source in the context of Directive 2002/46/EC. EFSA Journal, 22(3), e8656.
•  Fu, C., Huang, L., Lian, C., Yue, J., Lin, P., Xu, L., Lai, W., Gao, C., Li, C., & Long, Y. (2025). Effects of long-term magnesium L-threonate supplementation on neuroinflammation, demyelination and blood-brain barrier integrity in mice with neuromyelitis optica spectrum disorder. Brain Research, 1846, 149234.
•  Patel, V., Akimbekov, N. S., Grant, W. B., Dean, C., Fang, X., & Razzaque, M. S. (2024). Neuroprotective effects of magnesium: implications for neuroinflammation and cognitive decline. Frontiers in Endocrinology, 15, 1406455.