RESVERATROL 250mg + BioPerine®

High-quality resveratrol in a simple format

Resveratrol 250mg + BioPerine^® from EssentialSeries is a dietary supplement made with natural resveratrol and black pepper.

The formula combines 250mg of pure trans-resveratrol from a 200:1 dry extract of Fallopia japonica, with BioPerine^®, a standardized piperine extract that boosts its bioavailability. A quality choice to include in your daily supplement routine.

Just one veggie capsule a day, easy to fit into any routine.

Why choose trans-resveratrol 250mg?

The optimal form of resveratrol

Trans-resveratrol is the bioactive isomer of resveratrol, a stilbene found in plants like grapes or peanuts, especially concentrated in the root of Polygonum cuspidatum. The trans- version is the most stable and considered the highest quality from a functional perspective.

Its study has been linked to phenomena like the 'French paradox' (associated with longevity) and its use as an ingredient in supplements has become widespread among adults looking to support a varied and complete diet with high-quality nutrients.

The 250mg daily dose in our formula offers a balanced alternative for people wanting to add this nutrient to their routine, seeking a higher intake than options like resveratrol 120mg, but not as high as the 500mg option.

Fallopia japonica: standardized botanical source

The plant extract we use comes from the root of Fallopia japonica, also known as Polygonum cuspidatum. This species is widely used for its natural trans-resveratrol content, allowing precise nutrient standardization.

We chose this source because it is the richest option in natural trans-resveratrol, compared to others that may contain isomeric mixtures or lower nutrient concentrations.

The synergy of resveratrol with piperine

One of the main challenges of resveratrol is its limited bioavailability. To support its oral absorption, the formula includes BioPerine^®, the patented extract of Piper nigrum, rich in piperine.

BioPerine^® was developed by Sabinsa Corporation and is considered a benchmark ingredient in the field of functional extracts for its ability to support the absorption of certain plant constituents, like resveratrol.

We include 20mg of BioPerine^® per capsule, to guarantee a relevant dose of piperine (19,7mg), as validated in bioavailability studies:

• Johnson, J. J., Nihal, M., Siddiqui, I. A., Scarlett, C. O., Bailey, H. H., Mukhtar, H., & Ahmad, N. (2011). Enhancing the bioavailability of resveratrol by combining it with piperine. Molecular nutrition & food research, 55(8), 1169–1176.

The combination of both ingredients allows optimizing the bioavailability of trans-resveratrol.

Clean label: only what’s necessary

Our formula has been designed under the clean label standards that characterize our developments: no superfluous ingredients, no colorants, no aesthetic additives, coatings, etc. Just the essentials, in a simple veggie capsule suitable for vegans.

Just one capsule a day: easy and adapted to your healthy lifestyle.

What to combine it with?

Resveratrol is often used with certain types of compounds, although it’s compatible with all of them since it has no negative interactions with other supplements.

The most commonly used products alongside resveratrol are:

•  NADH.
•  Ubiquinol.
•  D-Ribosa.

References

•  National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 445154, Resveratrol.
•  Meng, X., Zhou, J., Zhao, C. N., Gan, R. Y., & Li, H. Bin. (2020). Health benefits and molecular mechanisms of resveratrol: A narrative review. Foods, 9(3).
•  Leis, K., Pisanko, K., Jundziłł, A., Mazur, E., Mȩcińska-Jundziłł, K., & Witmanowski, H. (2022). Resveratrol as a factor preventing skin aging and affecting its regeneration. Postepy Dermatologii i Alergologii, 39(3), 439–445.
•  Ramírez-Garza, S. L., Laveriano-Santos, E. P., Marhuenda-Muñoz, M., Storniolo, C. E., Tresserra-Rimbau, A., Vallverdú-Queralt, A., & Lamuela-Raventós, R. M. (2018). Health effects of resveratrol: Results from human intervention trials. Nutrients, 10(12).
•  Bohara, R. A., Tabassum, N., Singh, M. P., Gigli, G., Ragusa, A., & Leporatti, S. (2022). Recent Overview of Resveratrol’s Beneficial Effects and Its Nano-Delivery Systems. Molecules, 27(16). 
•  Brown, K., Theofanous, D., Britton, R. G., Aburido, G., Pepper, C., Sri Undru, S., & Howells, L. (2024). Resveratrol for the Management of Human Health: How Far Have We Come? A Systematic Review of Resveratrol Clinical Trials to Highlight Gaps and Opportunities. International Journal of Molecular Sciences, 25(2).